Sucralose (Splenda)

Why Do You Need to Know About Splenda?

Splenda, best known for its marketing logo, "made from sugar so it tastes like sugar,' has taken the sweetener industry by storm. Splenda has become the nations number one selling artificial sweetener in a very short period of time.

Between 2000 and 2004, the percentage of US households using Splenda products jumped from 3 to 20 percent. In a one year period, Splenda sales topped $177 million compared with $62 million spent on aspartame-based Equal and $52 million on saccharin-based Sweet 'N Low.

McNeil Nutritionals, in their marketing pitch for Splenda emphasizes that Splenda has endured some of the most rigorous testing to date for any food additive. Enough so to convince the average consumer that it is in fact safe. They claim that over 100 studies have been conducted on Splenda. What they don't tell you is that most of the studies are on animals.

Additional Concerns About Splenda Studies

There have been no long-term human toxicity studies published until after the FDA approved sucralose for human consumption. Following FDA approval a human toxicity trial was conducted, but lasted only three months, hardly the length of time most Splenda users plan to consume sucralose. No studies have ever been done on children or pregnant women.

Much of the controversy surrounding Splenda does not focus just on its safety, but rather on its false advertising claims. The competition among sweeteners is anything but sweet. The sugar industry is currently suing McNeil Nutritionals for implying that Splenda is a natural form of sugar with no calories.

Is It REALLY Sugar?

There is no question that sucralose starts off as a sugar molecule, it is what goes on in the factory that is concerning. Sucralose is a synthetic chemical that was originally cooked up in a laboratory. In the five step patented process of making sucralose, three chlorine molecules are added to a sucrose or sugar molecule. A sucrose molecule is a disaccharide that contains two single sugars bound together; glucose and fructose.


The chemical process to make sucralose alters the chemical composition of the sugar so much that it is somehow converted to a fructo-galactose molecule. This type of sugar molecule does not occur in nature and therefore your body does not possess the ability to properly metabolize it. As a result of this "unique" biochemical make-up, McNeil Nutritionals makes it's claim that Splenda is not digested or metabolized by the body, making it have zero calories.

It is not that Splenda is naturally zero calories. If your body had the capacity to metabolize it then it would no longer has zero calories.


How Much Splenda is Left In Your Body After You Eat It?

If you look at the research (which is primarily extrapolated form animal studies) you will see that in fact 15% of sucralose is absorbed into your digestive system and ultimately is stored in your body. To reach a number such as 15% means some people absorb more and some people absorb less. In one human study, one of the eight participants did not excrete any sucralose even after 3 days. Clearly his body was absorbing and metabolizing this chemical. That is what our bodies are supposed to do.


The bottom line is that we all have our own unique biochemical make-up. Some of you will absorb and metabolize more than others. If you are healthy and your digestive system works well, you may be at higher risk for breaking down this product in your stomach and intestines. Please understand that it is impossible for the manufacturers of Splenda to make any guarantees based on their limited animal data.


If you feel that Splenda affects you adversely, it is valid. Don't let someone convince you that it is all in your head. You know your body better than anyone else.

How to Determine if Splenda is Harming You

The best way to determine if Splenda or sucralose is affecting you is to perform an elimination/challenge with it. First eliminate it and other artificial sweeteners from your diet
completely for a period of one to two weeks. After this period reintroduce it in sufficient quantity.
For example, use it in your beverage in the morning, and eat at least two sucralose containing products the remainder of the day. On this day, avoid other artificial sweeteners so that you are able to differentiate which one may be causing a problem for you. Do this for a period of one to three days. Take notice of how your body is feeling, particularly if it feels different than when you were artificial sweetener free.

The entire issue of long-term safety has never been established. Let's look at the facts again:

1.  There have only been six human trials to date

2.  The longest trial lasted three months

3.  At LEAST 15% of Splenda is not excreted from your body in a timely manner

4.  Considering that Splenda bears more chemical similarity to DDT than it does to sugar, are you willing to bet your health on this data?

5.   Remember that fat soluble substances, such as DDT, can remain in your fat for decades and devastate your health.


From: www.Xylitol.com

Sucralose: What are the pros?

Sucralose is the newest nonnutritive sweetener on the market. It is most well known for its claim to be made from sugar. It is used alone or found in Splenda and is 600 times sweeter than sucrose (table sugar). When used alone, it provides essentially no calories and is not fully absorbed. In 1998, it was approved for limited use, and in 1999, it was given approval for use as a general-purpose sweetener. It is currently found in over 4,500 products, including foods that are cooked or baked. This artificial sweetener that can be used for cooking, so it has rapidly become one of the most popular and highly consumed artificial sweeteners.

The FDA reviewed studies in human beings and animals and determined that sucralose did not pose carcinogenic, reproductive, or neurological risk to human beings. The acceptable daily intake (ADI) for sucralose was set at 5 mg/kg of body weight/day. To determine your ADI, divide your weight in pound by 2.2 and then multiply it by 50. For example, if you weigh 200 lbs., your weight in kg would be 91 (200 divided by 2.2) and your ADI for sucralose would be 455 mg (91 x 5).

Sucralose: What are the cons?

The most misunderstood fact about sucralose is that it is nothing like sugar even though the marketing implies that it is. Sucralose was actually discovered while trying to create a new insecticide. It may have started out as sugar, but the final product is anything but sugar. According to the book Sweet Deception, sucralose is made when sugar is treated with trityl chloride, acetic anhydride, hydrogen chlorine, thionyl chloride, and methanol in the presence of dimethylformamide, 4-methylmorpholine, toluene, methyl isobutyl ketone, acetic acid, benzyltriethlyammonium chloride, and sodium methoxide, making it unlike anything found in nature. If you read the fine print on the Splenda web site, it states that "although sucralose has a structure like sugar and a sugar-like taste, it is not natural."

The name sucralose is misleading. The suffix -ose is used to name sugars, not additives. Sucralose sounds very close to sucrose, table sugar, and can be confusing for consumers. A more accurate name for the structure of sucralose was purposed. The name would have been trichlorogalactosucrose, but the FDA did not believe that it was necessary to use this so sucralose was allowed.

The presence of chlorine is thought to be the most dangerous component of sucralose. Chlorine is considered a carcinogen and has been used in poisonous gas, disinfectants, pesticides, and plastics. The digestion and absorption of sucralose is not clear due to a lack of long-term studies on humans. The majority of studies were done on animals for short lengths of time. The alleged symptoms associated with sucralose are gastrointestinal problems (bloating, gas, diarrhea, nausea), skin irritations (rash, hives, redness, itching, swelling), wheezing, cough, runny nose, chest pains, palpitations, anxiety, anger, moods swings, depression, and itchy eyes. The only way to be sure of the safety of sucralose is to have long-term studies on humans done.

Splenda is a product that contains the artificial sweetener sucralose, but that is not all that it contains. Sucralose does have calories, but because it is 600 times sweeter than sugar, very small amounts are needed to achieve the desired sweetness so you most likely won't consume enough to get any calories. The other two ingredients in Splenda are dextrose and maltodextrin, which are used to increase bulk and are carbohydrates that do have calories. One cup of Splenda contains 96 calories and 32 grams of carbohydrates, which is often unnoticed due to the label claiming that it's a no calorie sweetener. Because this is found in so many products and can be used in cooking, it can be possible to consume 1 cup or more each day. For people with diabetes, this is a significant amount of carbohydrates, and for people who are watching their weight, this can be a problem. Consuming an additional 100 calories a day can result in a weight gain of 10 lbs. per year!

A recent study found that Splenda affected the absorption of medications in rats. The rats were given sucralose at doses of 1.1-11 mg/kg. After 12-weeks, they found that the rats had half of the good bacteria in the gut. They also found that Splenda interferes with the absorption of prescription medications. Other research studies have come out to show that this is not what happens. The only way to know for sure is to perform long-term studies in humans. Unfortunately, this takes time. It can also be dangerous if this is actually happening. The limited number of studies and lack of long-term studies on sucralose means that we are going to have to learn things like this as we go.

From:www.medicinenet.com

Sucralose Side Effects
Despite approval of the FDA, many people surely suffer from the sucralose toxicity and several symptoms of sucralose allergy. Following are the various sucralose dangers.
  • Gastrointestinal problems like bloating, nausea and diarrhea
  • Skin irritations, rashes, hives, swelling and itching
  • Breathing difficulties, wheezing
  • Runny nose, cough
  • Palpitation, chest muscle pain, itchy eyes
  • Anxiety, depression, mood swings, sudden onset of anger
 

Apart from these, following are several other side effects of sucralose that can also be fatal and life threatening.

  • Enlarged liver and kidneys
  • Reduced growth rate
  • Atrophy of lymph follicles in the thymus and spleen
  • Increased cecal weight
  • Hyperplasia of the pelvis
  • Decreased fetal body weights
  • Decreased placental weights
  • Extension of pregnancy period
  • Decreased red blood cell count
  • Aborted pregnancy or stillbirth

  • From: www.Buzzle.com

 

Sometimes you just have to sit back and laugh at the absurd methods employed by the food industry to deceive and manipulate you. Take Splenda, for example. Their website now touts three new "improved" versions:

Splenda with:

  1. B vitamins
  2. Antioxidants
  3. Fiber

Of course, they claim these are "three smart new ways to sweeten" your food and drink. Nothing could be further from the truth. In fact, it's sheer unmitigated nonsense!  Splenda (sucralose), which is an artificial sweetener like aspartame, is likely to push your health in the wrong direction, and there'snothing smart about that…

Consuming artificial sweeteners can cause distortions in your biochemistry, and if you drink diet soda in an attempt to lose weight, they won't help you. Instead, most studies looking at this show very clearly that diet soft drinks actually double your obesity risk by stimulating your appetite, increasing carbohydrate cravings, and stimulating fat storage!

Several years ago, I wrote a book called Sweet Deception, in which I expose the many concerns related to the consumption of artificial sweeteners. It's an extremely well-researched book, and it's as valid today as it was when I first wrote it. I spent over three years and had five health care professionals work on it with me, as the maker of Splenda, Johnson & Johnson, had their legal firm write me a 20-page letter threatening to sue me if I published the book.  Needless to say, the book was published and they did not sue me as the information was all true.

Spenda is Not a Zero Calorie Product

Splenda uses a number of misleading tactics to sell their product. For starters, it is actually not a "zero calorie" sweetener.

Sucralose is about 600 times sweeter than sugar, so if it was sold by itself, they wouldn't be able to package it—each packet would contain just a couple of grains, which would be more than plenty to sweeten a cup of coffee. Hence they have to add a bulking agent, such as maltodextrin—which is a sugar!

So, about 99 percent of that packet of Splenda is a type of sugar, and only about one percent is actually sucralose. Each packet has four calories, but because the amount of sugar is less than one gram, they get away with saying it has "no calories" due to a loophole in the labeling law.

However, there's yet another reason why they can make this claim.

Sucralose is a synthetic chemical created in a laboratory. In the five-step patented process of making sucralose, three chlorine molecules are added to one sucrose (sugar) molecule.

Some will argue that natural foods also contain chloride, which is true. However, in natural foods, the chloride is connected with ionic bonds that easily dissociate.. But in Splenda, they're in a covalent bond that does not dissociate. In fact, there are NO covalent chloride bonds to organic compounds in nature—they only exist in synthetic, man-made form. Aside from Splenda, other examples of synthetic covalently bound chloride compounds include:

  • DDT
  • PCB's
  • Agent orange

Now, your body has no enzymes to break down this covalently bound chloride. Why would it? It never existed in nature, so the human body never had a reason to address it. And since it's not broken down and metabolized by your body, they can claim it to be non-caloric—essentially, it's supposed to pass right through you.

However, the research (which is primarily extrapolated from animal studies) indicates that about 15 percent of sucralose IS in fact absorbed into your digestive system, and ultimately stored in your body. This is a significant concern. One 2009 study found unmistakable evidence that Splenda is absorbed by fat, contrary to previous claims. They also discovered other disturbing health problems...

Splenda May Destroy Intestinal Flora

The animal study, published in the Journal of Toxicology and Environmental Health, found that Splenda:

  • reduced the amount of good intestinal bacteria by 50 percent
  • increased the intestinal pH level, and
  • affected a glycoprotein that can have crucial health effects, particularly if you're on certain medications

James Turner, the chairman of the national consumer education group Citizens for Health, expressed shock and outrage after reading the findings, stating that:

"The report makes it clear that the artificial sweetener Splenda and its key component sucralose pose a threat to the people who consume the product. Hundreds of consumers have complained to us about side effects from using Splenda and this study ... confirms that the chemicals in the little yellow package should carry a big red warning label."

I agree, because anytime you destroy healthy intestinal bacteria you open yourself up to unfriendly micro-organisms that can cause health problems. Your immune system, which is imperative for general health is dependent on healthy gut flora, so the idea that this artificial sweetener may destroy up to half of all your healthy gut bacteria is disconcerting to say the least.

Many people are already deficient in healthy bacteria due to choosing highly processed foods. This is why a high quality probiotic is one of the very few supplements I highly recommend for nearly everyone.

How Diabetics May Be Mislead

Artificial sweeteners like Splenda are commonly recommended for diabetics, since sucralose will not influence your blood sugar levels. However, what they fail to realize is that Splenda is not all sucralose… Remember, most of that packet is actually sugar—only about one percent is sucralose!

This may still not seem like a big deal, considering how little is in those packets. But many diabetics will use upwards of 10 packets or more a day, in various drinks and foods, and in high quantities it can have a significant impact in type 1 diabetics.

Safety Studies Sorely Lacking

Splenda is promoted as being a safe, well-researched product, but is it really?

If you look through the research literature, you'll find about 200 studies on Splenda/sucralose, and only about 10 percent of those have anything to do with safety. When I wrote Sweet Deception, there were only 15 studies relating to safety, and 13 of them were funded by the company that makes Splenda, leaving enormous room for conflict of interest!

In 1996, Dr. Ralph G. Walton, a professor of Clinical Psychiatry, reviewed 165 studies on aspartame, and discovered a remarkable discrepancy between study results and their source of funding. Of the 165 studies, 74 had industry related funding and 91 were independently funded.

Of those:

  • 100 percent of the industry funded studies supported aspartame's safety, while
  • 92 percent of the independently funded studies identified at least one potential health concern

However, Dr. Walton also pointed out that of the seven remaining non-industry funded studies, which supported aspartame's safety, six were done by the FDA, and the seventh was a literature review of mostly industry sponsored research. Considering the long-standing revolving door between various industries (especially Monsanto, which acquired G.D. Searle in 1985) and the FDA, it's questionable as to whether an FDA study can be considered truly "independent," even though they were counted as independent in Walton's review. If you give that concern any merit, you'd more or less be looking at 100 percent of industry related studies claiming aspartame to be safe, and 100 percent of independent studies flagging some sort of health concern...

This is truly powerful documentation of the influence of corporately sponsored trials on safety or any other potential complication that can occur!  This type of funding bias is a fatal flaw in the system, because in order to receive FDA approval, the product is not required to undergo any kind of independent study.

So what happens?

Well, we now know that in the drug industry, studies that do not support the drug are simply dismissed or thrown away, and only those reaching a favorable conclusion are presented. And there's nothing to indicate that the same tactics aren't also going on in the food industry.

Another troublesome issue is the fact that there are no long-term studies to evaluate the health effects of chronic exposure to sucralose. When I wrote my book, the longest safety study ever performed had lasted FOUR DAYS, and it looked at sucralose in relation to tooth decay, not human tolerance!

Potential Side Effects of Splenda

Going back to those 15 published safety studies on Splenda, only seven were done on humans. Two of these were published in respected peer-reviewed neurology journals, and they both showed a clear and strong association between the use of Splenda and migraine headaches.  Animal studies have also revealed a number of problems, such as:  

  • Decreased red blood cells -- sign of anemia -- at levels above 1,500 mg/kg/day
  • Increased male infertility by interfering with sperm production and vitality, as well as brain lesions at higher doses
  • Enlarged and calcified kidneys (McNeil stated this is often seen with poorly absorbed substances and was of no toxicological significance. The FDA Final Rule agreed that these are findings that are common in aged female rats and are not significant.)
  • Spontaneous abortions in nearly half the rabbit population given sucralose, compared to zero aborted pregnancies in the control group 
  • A 23 percent death rate in rabbits, compared to a 6 percent death rate in the control group 

With so few studies available, it may be safer to listen to consumer feedback…I've compiled a page on my web site, The Potential Dangers of Sucralose, where you can share your own experiences and side effects, as many others already have. In fact, the first-hand testimonies on this page already outnumber the amount of people included in all of Splenda's safety studies!

The symptoms are so numerous I can't include them all, but the following are common symptoms, usually noticed within a 24-hour period following consumption of a Splenda product:

Skin -- Redness, itching, swelling, blistering, weeping, crusting, rash, eruptions, or hives (itchy bumps or welts Lungs -- Wheezing, tightness, cough, or shortness of breath Head -- Swelling of the face, eyelids, lips, tongue, or throat; headaches and migraines (severe headaches)
Nose -- Stuffy nose, runny nose (clear, thin discharge), sneezing Eyes -- Red (bloodshot), itchy, swollen, or watery Stomach -- Bloating, gas, pain, nausea, vomiting, diarrhea, or bloody diarrhea
Heart -- Palpitations or fluttering Joints -- Joint pains or aches Neurological -- Anxiety, dizziness, spaced-out sensation, depression

How Dangerous is Splenda?

If you only use it on rare occasions, in all likelihood it is not going to harm you. It's only likely to become an issue if you're using large amounts on a regular basis. Remember, no one knows exactly what the long-term human health ramifications are, as the longest study conducted lasted a mere four days!

This means that you and your family are the guinea pigs when it comes to evaluating long-term safety… And for this reason, I strongly recommend applying the precautionary principle, especially for your children.

The most important principle I want to emphasize here is not so much the specifics of why Splenda is potentially toxic or harmful, but rather I want you to recognize the tactics employed by these companies to manipulate and deceive you. Once you understand the basics of how they manipulate you and distort science to prove their point, then you will know when to exert caution, and when to be skeptical about new products.

Just like the drug industry, many of the sales strategies used in the food industry aim to give you some magic bullet solution that veers from time-honored principles that our ancestors used to stay healthy. Once you know what those principles are, and you're aware of the sales tactics employed, you're in a position to make solid, informed decisions.

Health is really a simple process. By replicating the patterns of our ancestors, we can optimize our health. It's important to realize that our genes do not adapt very quickly to changes in our environment, and the human body simply is not designed to thrive on modern "food-like" substances made of synthetic chemicals not found in nature.

Your body is designed to maintain health, but when you expose it to toxic influences, and deprive it of nutritional support and the basic building blocks it needs to thrive, then you'll begin losing your vitality and veer toward disease and chronic, long-term health complications…

How to Kick the Artificial Sweetener Habit

Your body typically craves sweets when you're denying it the fuel it needs. Sugar (and grain carbs) is very quick fuel and can give your body a boost when it's running low. And contrary to popular belief, using artificial sweeteners does not trick your body into thinking it has had its fill; rather it wants more sweets because it didn't get the energy boost with that sweet taste!

A powerful solution to help curb your cravings is to determine your nutritional type, which will tell you which foods you need to eat to feel full and satisfied. It may sound hard to believe right now, but once you start eating right for your nutritional type, your sweet cravings will disappear. To help you turn your health around, I now offer the full nutritional typing program online for free, so please take advantage of this opportunity to dramatically change your health for the better.

Interestingly, nutrition- and fitness expert Ori Hofmekler recently shared a fascinating benefit of caffeine that can be helpful here. If you like coffee, drinking organic black coffee (meaning without sugar or milk) can help eliminate sugar cravings because the caffeine is anopioid receptor antagonist.

As you may know, sugar binds to the same opioid receptors as cocaine and other addictive substances. But once an opioid receptor antagonist occupies that receptor, it prohibits you from becoming addicted to something else. Therefore, caffeine may attenuate the addictive impact of sugar. There are a few caveats to using this strategy however, including:

  • Only drink organic coffee (as it's one of the most pesticide-heavy crops there are)
  • Drink it black, sans sugar/artificial sweeteners or milk
  • Only drink coffee in the morning, prior to exercise
  • Limit your consumption to one or two cups

In addition to eating right for your nutritional type, I highly recommend addressing the emotional component of your food cravings, using a tool such as the Emotional Freedom Technique (EFT). It's one of the most profoundly effective tools I've ever used or researched to help overcome food cravings and reach dietary success. Turbo Tapping is particularly useful if you're addicted to soda. It's an extremely effective and simple tool to get rid of your addiction in a short period of time.

From:  www.mercola.com


 

 

 

 

   

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